10 Best CBD Oil for Arthritis Pain to Buy: Uses, Effects, & Benefits

But as arthritis becomes a bigger problem, new and experienced CBD users want to find the best CBD oil for their needs.

After careful examination of newer and known brands, we’ve compiled the 10 best CBD oil for arthritis that may help provide relief.

It’s important to note that we always recommend consulting with your doctor to receive the best and most accurate information. Just like any other health supplement, cannabidiol may have risks involved.

How Effective Is CBD at Treating Arthritis?

The jury is still out about whether CBD can help with relief from arthritis symptoms. But there are a lot of animal studies pointing us in that direction.

If those studies provide similar results in human trials, we could hope that CBD is somewhat effective at reducing arthritis symptoms.

Keep in mind, CBD can’t cure arthritis, nor is it a recognized treatment by the Food and Drug Administration (FDA). However, what we see so far is very promising.

We’ll cover that in greater detail later.

Top 10 CBD Oils for Arthritis to Buy in 2022

We applied our key benchmarks to several CBD oil tincture vendors, narrowing them down to the top 10 options. These companies made it on our list because they went above and beyond the basic standard for CBD products.

The brands we’ll cover for best CBD oil for arthritis today (in order of preference) are:

1. Colorado Botanicals - Best CBD Oil for Arthritis
2. Joy Organics
3. NuLeaf Naturals
4. Charlotte’s Web
5. Plus CBD
6. cbdMd
7. CBdistillery
8. Lazarus Naturals
9. Fab CBD
10. Koi CBD

Factors That Helped Us Rank for the Best CBD Oil for Arthritis

Although the FDA’s recent crackdown on unscrupulous vendors did drive an overall improvement in self-regulation and quality, many brands try to cut corners. But thanks to effective marketing, they can take mediocre CBD products and make them sound top tier.

Sifting through all the vendors isn’t something you’re keen on doing. So we decided to take a deep look into which brands deserve recognition for their quality, transparency, and overall reputation.

We scoured the CBD industry for the best companies and CBD products, applying a list of specific benchmarks to narrow down the list.

These objective characteristics help ensure that the CBD you choose for arthritis symptoms is right for you.

1. Farming Practices

The quality of hemp heavily depends on the way it’s grown. In turn, that quality translates to the hemp extract used in a variety of CBD products.

In our effort to evaluate farming practices, we examine the following:

• Hemp source: USDA certification? Organic? Organically grown?
• Grown in-house: Where do they get their hemp? Locally grown or an outside producer?
• Sustainability: Is the vendor’s hemp grown using environmentally friendly methods?

2. Extraction and Purification

The extraction method is a critical benchmark for us. Some ways are cleaner or more effective than others, while other brands may have their proprietary approach to their hemp extract.

We base this benchmark on three key points:

• Extraction: CO2, alcohol, butane, etc.
• Facilities: Is the CBD extracted, processed, and tested by a third-party lab?
• Knowledge: Does the brand employ medical and pharmaceutical experts?

3. Quality and Efficacy

The CBD we choose needs to be well made but also effectively address the pain and inflammation from arthritis. We therefore examine:

• Potency: CBD per volume or weight.
• CBD option: Full-spectrum, broad-spectrum, or pure CBD isolate?
• Contents: Natural ingredients? Any added flavors, colors, nutrients, or supplements?

4. Flavor

Although not essential, flavor (or lack thereof) can improve or harm the overall experience. CBD products for arthritis that taste good are easier to take. If a brand offers flavored products, we take a close look at:

• Variety: Are there a lot of flavor options?
• Choices: Do the flavors offered taste good, or do they sound appealing?
• Flavor strength: Do they cancel out the cannabis taste?

5. Third-Party Lab Testing

If there’s anything we need to have, it’s third-party testing. Any brand that doesn’t test its products or provide certificates of analysis is a huge red flag. In addition, lack of testing indicates a potentially hazardous lack of transparency, so no company makes our list if they don’t perform this vital step.

We then base our evaluation on the results of those tests, specifically:

• Contamination: Are microbes, heavy metals, chemical pesticides, or other toxins present?
• Other compounds: Does the CBD contain a diverse profile of terpenes and cannabinoids?
• Label accuracy: Does CBD content in the tests match the label?

6. Reputation

Not every brand has had a chance to build a significant reputation, which isn’t a huge problem given the other benchmarks we have. But a CBD vendor that’s well-received by customers speaks volumes beyond the company’s CBD product claims and descriptions.

To get an idea of where a CBD brand stands, we examine two key areas:

• User reviews: Online opinions from independent sources.
• Industry presence: Is the vendor reputable? Are they known for their quality?

7. Shipping and Returns

Some vendors offer free shipping (conditions may apply) and extensive guarantees. While we prefer companies with lenient shipping and return policies, it’s not a qualifying factor.

10 Best CBD Oils for Arthritis: Reviews

In the following section, we will cover the best CBD oils for arthritis that you can buy in 2022. With our in-depth review of many companies, we’re confident that these products are the best out there.

1. Colorado Botanicals - Best CBD Oil for Arthritis

Colorado Botanicals was established in 2017 with the intention of becoming a top-tier CBD oil vendor. Fast-forward to 2022, and Colorado Botanicals now sells some of the most potent, pure CBD oils we’ve seen.

Colorado Botanicals is an example of hemp CBD done right, from their sourcing and growing to manufacture testing.

Colorado Botanicals was also featured in Discover Magazine’s article on Best CBD for Inflammation to buy in 2022, which helped put them at the top of our list, and after a thorough review, it was a no-brainer to put them first.

Why Colorado Botanicals Is Our Top Pick for Arthritis

First and foremost, the quality and measures Colorado Botanicals takes to produce their hemp extract surpasses what any other brand does based on our research and review.

Colorado Botanicals uses their proprietary extraction and purification process, taking a pharmaceutical approach to separate cannabinoids and terpenes from the hemp oil and, more importantly, naturally retaining terpenes in the process.

Colorado Botanicals also doesn’t play around when it comes to hemp. Everything is sourced from organic plants grown using sustainable farming practices. They emphasize how the better quality the hemp genetics are, the better the cannabinoid and terpene profile will be.

Hemp quickly absorbs toxins from the surrounding environment, which is why Colorado Botanicals works diligently to keep that area free of contaminants, checking the soil and air quality for any early warning signs. Not only is this handy for nipping a problem in the bud, but it also guarantees the cleanest product possible.

They even back their products with a 60-day satisfaction guarantee. So if you’re not happy with the product within 60 days, you can get a full refund.

Not only do they test their hemp oil multiple times in-house, but once production is complete, Colorado Botanicals has FESA Labs and ProVerde Laboratories conduct third-party testing on every batch, with certificates of analysis available on their website.

All Colorado Botanicals CBD products are broad-spectrum, meaning a full cannabinoid and terpene profile while being THC-free.

Terpenes: The Colorado Botanicals Difference

Terpenes come up a lot when addressing CBD oil because they’re an integral part of what separates good products from excellent ones.

This is one of the many things that separates Colorado Botanicals from the vast majority of brands out there. Their unique proprietary purification process uses low heat, which avoids burning off terpenes.

Below is an image we took from their third-party lab report of their terpene profile test. We’ll cover two terpenes associated with helping symptoms of arthritis.

Beta-caryophyllene

Beta-caryophyllene (β-Caryophyllene) is a terpene native to different spicy plants, like cinnamon or black pepper.

Interestingly, this compound appears to behave like a cannabinoid, acting on the CB1 and CB2 receptors, according to one 2020 study.

The above publication noted the terpene’s anti-inflammatory and analgesic effects in rats.

Linalool

Third-party tests show a substantial amount of linalool in Colorado Botanicals CBD oil. This is impressive, given how rare linalool is in large quantities. Usually, you’ll find it in strong-smelling plants, like lavender.

A 2017 review examined the terpene research from various studies, explaining how linalool helps reduce pain and inflammation in rodent test subjects.

Top Products

Colorado Botanicals carries four CBD oil tincture options available in peppermint or unflavored that we prefer for arthritis. CBD concentrations range from 300 mg to 3,000 mg in a single 30 mL bottle. However, if you want to address arthritis symptoms specifically, we suggest the following two products. Their CBD gummies are also another great option.

Colorado Botanicals 750 mg Broad-Spectrum CBD Oil

The 750 mg oil is a great starting point. With a CBD potency of 25 mg per 1 mL, this product offers outstanding value, outdoing many of its rivals.

Created with broad-spectrum CBD, this tincture is THC-free, using extract suspended in natural MCT coconut oil. Thanks to a closely monitored hemp growing and testing process, you won’t find added terpenes, solvents, or artificial ingredients.

Colorado Botanicals 1,500 mg Broad-Spectrum CBD Oil

With 1,500 mg of CBD per bottle and delivering an impressive 50 mg per 1 mL, this oil is two times more potent than the 750 mg option ― but not twice the price.

Ingredients are identical, but the 1,500 mg CBD product offers more value than the 750 mg option.

2. Joy Organics

Joy Organics is a fantastic vendor for many reasons. Founded by married couple Joy and Todd Smith, the company has a solid reputation in the CBD industry.

The company’s oils are decently potent, ranging from 30 to 75 mg per 1 mL in each 30 mL bottle. You also have a choice between five flavors: unflavored, fresh lime, tranquil mint, summer lemon, and orange bliss.

Joy does an excellent job adhering to many of the core benchmarks we want to see in any reputable CBD company.

What We Love About Joy Organics

Joy Organics can legally state their domestic hemp is USDA Certified Organic. This is different from simply saying a product is organic or organically grown. It’s a legal regulatory stamp of approval stating a product contains at least 95% organic ingredients. If you want purity in sourcing, Joy Organics hits the mark. Oils are available in full-spectrum and broad-spectrum options, in case some people are concerned about THC content but still want the benefits of other plant compounds.

The company says they use a proprietary CO2 extraction process (like Colorado Botanicals) to maximize terpene, cannabinoid, and flavonoid retention. In addition, third-party test results are available on each product page for reference.

Joy is one of the cheaper options we’ve seen, with the most expensive item retailing for $129.95. The savings are even better if you take advantage of their 25% discount for subscribers.

They also have an excellent return policy. You can return used or unused products within 30 days for a full refund.

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Joy Organics Full-Spectrum 1,350 mg CBD Oil

If you decide to go with Joy Organics, we suggest their Full-Spectrum 1,350 mg Fresh Lime Organic CBD Tincture if you need relief from arthritis, with an added benefit of 0.3 percent THC.

With 45 mg per 1 mL, this oil’s moderate potency is a good starting point but can also do the job for more advanced arthritis relief.

The full-spectrum extract is suspended in organic MCT oil, with organic key lime oil and organic stevia for flavor and sweetening.

The key lime taste goes a long way to disguising the otherwise powerful full-spectrum “hempy” taste.

3. NuLeaf Naturals

A CBD veteran, NuLeaf Naturals has been going strong since its founding in 2014. They’re comparable to Colorado Botanicals, with a strong focus on organic growing, clean extraction, and purity.

NuLeaf’s commitment to all-natural CBD oil tinctures means they use only full-spectrum CBD (whole plant) extract in their product, with no added flavors or fillers.

CBD choices range from 300 mg to 6,000 mg, with a 60 mg per 1 mL concentration across the board.

The price might also be a sore spot for some. You can get a comparable or better oil at Colorado Botanicals for around $40 less.

Still, you do get what you pay for. NuLeaf may not be first on our list, but they have more than earned their spot in third.

What We Love About NuLeaf Naturals

NuLeaf Naturals full-spectrum has a lot to offer beyond just CBD. As full-spectrum whole-plant extracts, you’ll get a full lineup of cannabinoids and terpenes, including less than 0.3 percent THC.

They also frequently put products on sale, so there’s a good chance you can snag one. NuLeaf is popular among customers for the very reasons we listed above.

The company brings everything to the table ― CO2 extraction, third-party testing, and an all-natural approach ― which showcases NuLeaf’s dedication to quality and safety.

Should you decide to become a regular customer, don’t forget to take advantage of their 10% discount for subscribing.

But if you want to see how NuLeaf stands out, just look at their products.

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Nuleaf Naturals Full Spectrum 1,800mg CBD Oil

We recommend NuLeaf Naturals 1,800 mg Full-Spectrum CBD Oil tincture. Like the other oils, it provides 60 mg per 1 mL. Containing 30 mL of oil per bottle, this is big enough to last you a while if you’re just starting to use CBD for arthritis.

As a bonus, NuLeaf chooses virgin organic hemp seed oil as its carrier. Hemp seeds and hemp seed oil are considered healthy foods and come packed with vitamins, minerals, and healthy fats.

4. Charlotte’s Web

Established in 2012, Charlotte’s Web offers a variety of full-spectrum hemp CBD tinctures. Oils come in both full-spectrum and CBD isolate options ranging in CBD potency from 7 mg per 1 mL to 60 mg per 1 mL. Bottle sizes also vary, with choices from 10 mL to 100 mL.

What We Love About Charlotte’s Web

Charlotte’s Web markets itself as “the most trusted hemp extract,” with a massive group of staunchly loyal customers who would back up that claim.

The company grows its hemp in-house, where it’s monitored from seed to sale ― much like how Colorado Botanicals maintains quality control. All hemp is organically grown and U.S. Hemp Authority Certified.

Charlotte’s Web also goes the extra mile with its savings. Aside from the 25% subscriber discount for regular customers, the vendor also gives 15% off to veterans who can confirm their status.

Despite solid brand credibility, Charlotte’s Web doesn’t act like the Nike of the CBD industry. Its products are incredibly affordable, with the most expensive 30 mL item costing $119.99. But this reduces to $89.99 if you take advantage of the enormous 25% discount for subscribers.

Charlotte’s Web is leaning toward CO2 extraction, but their older formula oils use isopropyl alcohol.

You’ll also notice a diverse array of terpenes and cannabinoids thanks to their full-spectrum or broad-spectrum extracts.

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Charlotte’s Web Original Formula 50mg CBD Oil

For CBD for arthritis, we recommend Charlotte’s Web Original Formula CBD Oil. Available in 30 mL and 100 mL options, each bottle offers 50 mg per 1 mL of CBD, making it strong enough to last a while for mild to moderate arthritis flare-ups but also sufficient for more severe symptoms.

Charlotte’s Web infuses this full-spectrum tincture into olive oil, which does little to reduce the “hempy” taste. However, the product is also available in mint chocolate for those who need some flavor.

5. PlusCBD

Originating in 2012, PlusCBD markets its products as “the most reliable hemp extracts on Earth.” The brand was founded by CV Sciences, a company with years of experience in the dietary supplement niche.

One sore spot for us is that the company doesn’t source its hemp from the European Union. They claim that this is due to logistical issues caused by regulatory roadblocks in the U.S.

Oils are available in 30 mL and 55 ml bottles and range from 8 mg per 1 mL to 25 mg per 1 mL for their 1,500 mg “Max Strength” oil. You can also choose between peppermint or unflavored options.

What We Love About PlusCBD

PlusCBD has some strong points. First, they use full-spectrum extract, which ensures the best effects possible, especially given the limited CBD.

Thanks to CO2 extraction, PlusCBD (and its customers) can make the best of its full-spectrum CBD.

PlusCBD also has an innovative approach to their oil, creating a spray pump mechanism for micro-dosing. Each pump contains a premeasured amount of oil, so you’ll need several sprays to reach the one-milliliter mark.

Their retail prices are a bit steep. For instance, the company’s 1,500 mg CBD is $119.99. Meanwhile, you can get the same amount of CBD with twice the concentration from Colorado Botanicals for $109.99

However, PlusCBD’s return policy is pretty good, with customers being given 30 days to return the product for a refund.

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+PlusCBD 1,500 mg CBD Drops

If you want to try PlusCBD for arthritis, we recommend the +PlusCBD 1,500 mg 55 mL Drops. Suspended in extra virgin olive oil, this product is excellent for micro-dosing.

However, with 25 mg of CBD, it probably won’t cut it for people with more severe symptoms. Unfortunately, it’s the strongest option.

6. cbdMD

Arising in 2015, cbdMD is a shining example of success in the CBD industry. They offer a broad range of potent CBD oils in 30 mL and some 60 mL options, available in natural, berry, orange, and mint flavors.

What We Love About cbdMD

cbdMD’s approach is similar to Colorado Botanicals, where concentration per serving doesn’t decrease with volume. What’s truly impressive is that these 30 mL bottles offer 300 mg to 7,500 mg of CBD. This means the highest option contains 250 mg per 1 mL.

All of their hemp is organically sourced from U.S. hemp farmers for the best quality extract possible.

The company’s products are very inexpensive compared to other vendors on our list. If that isn’t enough, they offer discounts of 30% to veterans and first responders, while disabled customers get 40% off.

cbdMD uses broad-spectrum extract, with CBN and CBG added during the process. You get a good variety of terpenes, with some additional cannabinoids. The company says they use a “proprietary extraction process” but doesn’t elaborate any further.

We also appreciate cbdMD’s 60-day guarantee, which includes a prepaid shipping return label.

They also offer a 30% discount on your first auto-ship order.

With all this in mind, it’s no surprise cbdMD has such fantastic customer feedback.

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cbdMD 750mg CBD Oil

The cbdMD Premium 750 mg CBD Oil Tincture is an excellent choice for arthritis patients. The product is identical to Colorado Botanicals, including the price ($59.99).

Packing 25 mg per 1 mL suspended in organic MCT oil, the 30 mL bottle is a good starting point if you’re new. Should your needs be more substantial, there are plenty of potent, equally affordable options.

The only thing that we feel doesn’t put this on par with Colorado Botanicals is the ambiguous extraction process, which costs them points in transparency.

7. CBDistillery

Established in 2016 and based in Denver, Colorado, CBDistillery follows many of the good practices you’d expect from top-tier CBD vendors.

Their CBD oils come in 30 mL bottles and contain between 500 mg and 5,000 mg of CBD. Oils are available in all three varieties ― full-spectrum, broad-spectrum, and pure CBD isolate.

Some include additional cannabinoids, specifically CBG, CBN, or both. Interestingly, CBN has analgesic and anti-inflammatory properties, while CBG may be effective for pain relief.

What We Love About CBDistillery

CBDistillery full-spectrum CBD sources its extracts from Colorado-grown industrial hemp “using natural farming practices.” In other words, you won’t find traces of chemical pesticides or fertilizers. Furthermore, they’re certified by the U.S. Hemp Authority. However, they’re not listed as “organic.”

The vendor uses CO2 extraction for maximum terpene retention and purity, while the final product is tested by a third-party lab to confirm CBD contents and detect potential contaminants.

All of the company’s CBD oils are very affordable, but those with CBG and CBN added cost more. Veterans and active military personnel can offset the cost with CBDistillery’s 30% discount.

CBDistillery full-spectrum CBD offers an excellent 60-day money-back guarantee. In most cases, you don’t even have to return the unwanted product. However, their fine print states that you can only request a refund or credit for your first purchase, likely to avoid people exploiting the no-return requirement.

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CBDistillery Extra Strength CBN + CBD Sleep Tincture

We strongly suggest trying the CBDistillery Extra Strength CBN + CBD Sleep Tincture. Aside from 900 mg of CBD (30 mg/mL), it also contains 300 mg (10 mg/mL) of CBN. As we mentioned, CBN may further help people with arthritis.

8. Lazarus Naturals

Founded in 2014 by Sequia Price (CEO), Lazarus Naturals is a Seattle-based hemp CBD vendor that grows its plants in Oregon.

Aside from full-spectrum CBD and isolate options, Lazarus naturals also offers pure CBG oil and CBG oil mixed with CBD ― something a growing number of companies embrace.

Full-spectrum CBD oil choices are limited, with only 20 mg/mL (standard potency) or 50 mg/mL (high potency) available.

What We Love About Lazarus Naturals

Lazarus Naturals uses organic hemp grown on their domestic farms. This practice ensures no traces of chemical pesticides or fertilizers.

What stands out about Lazarus Naturals is its meager cost. Their largest bottle ― 120 mL at 50 mg/mL ― retails for just $60. This is due to their use of the much cheaper isopropyl alcohol extraction method.

CO2 extraction is the ideal method because it’s much cleaner than alcohol. However, the company subjects its products to third-party tests, ensuring solvent traces are minor to non-existent.

We also need to mention their use of organic hemp seed and organic coconut MCT oil. Hemp seeds are often considered superfoods because of how rich they are in nutrients, but they contain no CBD.

Lazarus Naturals also has one of the best return policies possible. You can return your unwanted items for free with a prepaid shipping label up to 90 days after you receive them.

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Lazarus Naturals High Potency 1,500mg

Whether you’re new or experienced, the Lazarus Naturals High Potency 1,500 mg full-spectrum tincture is a good option. Available at 50 mg/mL, it’s not the most potent CBD oil available on the market. However, this full-spectrum tincture still offers a high enough potency for many consumers.

You can choose between four flavor options: classic (unflavored), chocolate mint, French vanilla mocha, and yuzu.

9. Fab CBD

Fab CBD is no stranger to the spotlight, with its products featured in publications like Forbes, L.A. Weekly, and Business Insider. Even the Make A Wish Foundation backs them. The media attention is well deserved, with each 30 mL bottle containing between 300 mg and 2,400 mg (10 mg/mL to 80 mg/mL) of CBD. You can choose from citrus, mint, berry, vanilla, or unflavored oils.

What We Love About Fab CBD

Fab CBD sources its hemp from Colorado using CBD organic growing methods ― no unwanted chemical fertilizers, pesticides, or herbicides.

Each oil product is made with full-spectrum extract for a robust profile that provides the best relief from arthritis.

The vendor also uses CO2 extraction and subjects its products to third-party tests through ProVerde, one of the labs trusted by Colorado Botanicals.

Fab CBD is a bit expensive, but we can let that slide because of their 30-day guarantee, even on unopened products (restrictions apply).

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Fab CBD 1,200mg CBD Oil

New and experienced consumers should consider the Fab CBD 1,200 mg Oil. The product provides a solid 40 mg/mL of CBD.

Suspended in MCT oil and containing all-natural flavors (if any), this full-spectrum oil might be worth a try if you have arthritis.

10. Koi CBD

Koi CBD is easily the most diverse company on our list. Aside from tinctures, they offer an array of popular CBD options, like e-liquids, drinks, inhalers, hemp flower joints, delta-8, and more.

Bottles are available in 30 mL (250 mg to 2,000 mg) and 60 mL (1,500 mg to 3,000 mg). However, they are a lot more expensive than many vendors.

What We Love About KOI CBD

Koi CBD’s hemp is organically grown in the U.S. ― so the usual benefits of clean sourcing apply here. They keep this momentum going through clean CO2 extraction, followed by third-party lab tests, which are readily available on their website.

Aside from the usual points, we notice Koi outdoes all the other vendors on our list regarding CBD oil choices. Aside from a broad range of sizes and potencies, all of their flavors are delicious, available in strawberry, peppermint, spearmint, lemon-lime, orange, and unflavored.

Koi CBD uses their proprietary Koi PRIZM broad-spectrum extract, retaining valuable terpenes and cannabinoids without any THC, suspended in MCT oil.

Although the company’s products are relatively expensive, you can get a 10% discount for subscribing.

Koi also offers a 25% discount to U.S. military veterans.

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Koi Naturals Hemp Extract CBD Oil Tincture 2,000mg

If you want a good balance between high potency and volume, consider Koi Naturals Hemp Extract CBD Oil Tincture 2,000 mg. Containing 66 mg/mL of CBD, this oil is strong enough to do the job for most arthritis patients.

The available flavors also make the “hempy” broad-spectrum taste a lot more palatable.

How CBD Oil Combat Arthritis Pain: Complete Guide

CBD oil is famous among people seeking arthritis pain management. While research is still ongoing, many swear by it ― and they’re likely onto something.

But if you’re new to CBD oil, chances are you have some questions. Before investing in CBD oil, it’s critical to understand it. The following guide covers all the essential information you need to know about CBD oil.

What is CBD Oil?

CBD oil is a convenient way to measure and ingest CBD quickly. It mainly consists of CBD extract and a carrier oil, but there are other potential contents.

Let’s break down the main ingredients.

CBD Extract

Cannabidiol (CBD) extract is CBD that’s been processed and separated from the cannabis plant (in this case, industrial hemp).

This non-intoxicating cannabinoid forms the backbone of every CBD product. Other plant compounds may also be present, depending on the CBD oil.

Carrier Oil

The carrier oil is a fatty substance infused with CBD extract. High-quality CBD vendors use oils like MCT oil, coconut oil, or hemp seed oil.

Lipids draw out and retain cannabinoids, which is why we need this ingredient.

Other Ingredients

Some products are processed to retain additional compounds, but terpenes are still lost during extraction. Some manufacturers might add terpenes after production.

This is one of the things that puts Colorado Botanicals at the top of our list. Their proprietary process maximizes natural terpene retention, so there’s no need to add them artificially.

Many vendors also offer flavored options, so some products may contain naturally or artificially derived flavors.

Types

CBD oil is available in three categories. We’ll look at those in detail later. For now, the choices are:

• Full-spectrum - Less than 0.3% THC
• Broad-spectrum - THC-Free CBD
• Isolate - Pure CBD

How Does CBD for Arthritis Work?

CBD’s mechanism of action is pretty well understood. But its relationship with various pathways in our bodies is far-reaching and complex, setting it apart from most major cannabinoids.

The Endocannabinoid System

The endocannabinoid system (ECS) is a massive network of receptors located in various parts of the body. The first type, known as CB1, appears mainly in the brain and spinal cord. Another group, called CB2, dominates the peripheral nervous system and the immune system.

The discovery of the ECS allowed us to understand endocannabinoids. These are cannabinoids produced by our bodies. One example is anandamide, an endocannabinoid similar in structure to THC.

Endocannabinoids play a critical role in maintaining “homeostasis.” This is a fancy word for “internal balance,” both physical and mental.

Phytocannabinoids refer to cannabinoids found externally, like CBD or THC.

How Does CBD for Arthritis Work

Some phytocannabinoids bind to both endocannabinoid receptors (THC being one example). Others specifically target one receptor. However, CBD doesn't bind directly to either one.

The ECS may not feel an affinity for CBD, but cannabidiol still indirectly affects the CB1 and CB2 receptors through other pathways.

The Endocannabinoid System

CBD doesn't have an affinity for the CB1 or CB2 receptors, but that doesn’t mean they don’t notice its presence.

When the endocannabinoid receptors detect CBD, they don’t respond by binding to it. Instead, their shape and function change. Despite not having a direct relationship with the ECS, CBD’s alterations of those receptors cause them to behave differently.

Once CBD does its work, the ECS may react differently to some cannabinoids or cripple their effects.

THC, for instance, is seriously hampered by CBD. Cannabidiol blocks the reuptake of THC in the ECS receptors. This dampening effect significantly reduces the intensity and duration of a THC high.

Other Receptors

CBD reportedly may help people with arthritis alleviate a vast list of symptoms, including pain and inflammation from arthritis. But these effects primarily have nothing to do with the endocannabinoid system but rather other essential receptors, including:

• Serotonin receptors
• TRPV1 vanilloid receptors
• GPR-55 orphan receptors
• PPAR receptors

However, let’s stop and focus on the TRPV1 receptor. CBD’s effects on this vanilloid receptor mitigate pain and inflammation. Reducing the inflammatory response and resulting discomfort makes CBD an excellent supplement for arthritis. Topical CBD is a great option for these purposes as well because you apply it directly to the area that needs it most.

What Studies Say About CBD Oil for Arthritis Pain

Arthritis is highly prevalent in the United States. According to the CDC’s most recent statistics, arthritis cases rose from 46 million to 54 million between 2004 and 2014.

The organization's projections showed a steady increase in cases, going from 63 million in 2020 to 78 million in 2045.

With CBD gaining traction as an alternative way to relieve arthritis symptoms, experts want to see any substance to these claims.

CBD and Inflammation

In the case of arthritis, inflammation forms the bedrock for other associated symptoms, especially pain. Getting rid of this swelling response is necessary to relieve other issues arising from arthritis.

It’s important to note that the Food and Drug Administration (FDA) has not approved CBD as a treatment for arthritis or rheumatoid arthritis cases.

However, there are a handful of preliminary studies that could support CBD’s anti-inflammatory properties.

For instance, one review looked at many of CBD’s anti-inflammatory effects when administered to mice with collagen-induced arthritis (CIA). Interestingly, they noted that CBD has anti-inflammatory and immunosuppressive properties, with both playing a crucial role in fighting arthritis inflammation. According to section 6.1 of the publication:

“The authors [of the CIA study] concluded that the ‘data show that CBD, through its combined immunosuppressive and anti-inflammatory actions, has a potent anti-arthritic effect in CIA.’”

Another study examined pancreatic inflammation in rat model of arthritis. This is a severe condition, indicating an immune response is demolishing healthy insulin-producing cells. Consequently, this can lead to Type 1 (T1D) diabetes in those mice.

Although the mice eventually developed diabetes, the study noted that CBD reduced the harmful immune response, reducing inflammation. The CBD’s action delayed the onset of T1D.

Researchers took another look at CBD’s anti-inflammatory properties in a 2017 study. Their experiment involved rats with osteoarthritis.

The scientists used topical application rather than oral administration. According to the paper, CBD effectively reduced acute joint inflammation when applied directly to the affected area.

CBD and Arthritis

Inflammation and pain typically go hand-in-hand. It’s not uncommon for arthritis inflammation studies to show analgesic effects as well.

“The data presented here indicate that local administration of CBD blocked OA pain. Prophylactic CBD treatment prevented the later development of pain and nerve damage in these OA joints. These findings suggest that CBD may be a safe, useful therapeutic for treating OA joint neuropathic pain.”

In other words, CBD was not just demonstrably effective against osteoarthritis pain but also might prevent the condition from worsening.

In 2018, researchers published a study demonstrating CBD’s interaction with the TRPV1 receptor we mentioned earlier. Although it was studying epilepsy patients, the impact on these vanilloid receptors is irrefutable - as we can see from the FDA’s eventual approval of Epidiolex.

Since TRPV1 receptors also control inflammation and pain, this study is as compelling and applicable to arthritis patients as to any other condition.

There was also an extensive review of CBD’s potential effects on arthritic joint pain and inflammation, where the authors concluded:

“CBD...has shown promise in mouse model studies by attenuating pro-inflammatory immune responses. Additionally, recent research has demonstrated the efficacy of CBD in decreasing the endogenous pain response in mice subjected to acute arthritic conditions….”

However, they also remind us that, while many animal studies exist, we still don’t have any human trials regarding the potential musculoskeletal benefits of CBD.

Choosing CBD Oil Companies: How to Buy from the Best Company

If you want to expand your CBD shopping beyond our top 10 vendors, there are a few things we recommend you look for.

Customer Reviews

We value customer feedback because it’s the most genuine source of information. There will always be unhappy clients, but if most people are happy with a vendor, that’s a good sign.

Background Checking

It’s helpful to perform your due diligence before jumping on board with any CBD vendor. For instance, if a company has been in trouble for mislabeling or making false claims, it should raise red flags.

Choose the CBD that Fits You Best

This is a no-brainer but easy to overlook in the sea of other considerations. Part of this means educating yourself on which compounds can help with arthritis.

Choosing the best CBD with terpenes and cannabinoids may help with the symptoms of arthritis, so try to find that information in the vendors’ third-party tests

Best Way to Use CBD Oil for Arthritis

Simply ingesting CBD oil is reportedly helpful against arthritis symptoms. Cannabidiol’s anti-inflammatory properties are effective at reducing and preventing the often immobilizing pain or swelling.

But taking CBD oil orally isn’t your only option for arthritis. There are two ways to see results associated with arthritis symptoms.

The product you use should be based on what fits your needs, depending on the symptoms you hope CBD can address.

But taking CBD oil orally isn’t your only option for acute problems like arthritis. There are two ways to achieve symptom relief.

Neither option is better than the other ― it’s based on what fits your needs. It’s not necessarily about finding the “best” consumption method for arthritis but rather the option that works best for you.

Ingestion

CBD oil is an edible hemp extract. When taken regularly, its consistent presence in your system may help prevent or reduce flare-ups. This option is convenient if you experience chronic arthritis discomfort.

However, this product takes at least 30 minutes before you feel the effects, so it’s not as efficient if you experience occasional arthritis episodes.

Topical CBD

While topicals are available, you can easily make your own with CBD oil. Just take some skin cream, lotion, or coconut oil, then mix it with a pre-measured amount of CBD extract.

During a flare-up, apply the topical to your affected area. Many consumers report virtually instant relief from both inflammation and pain.

This is a great way to stretch out your CBD oil supply (and save money) to be used as needed, rather than consumed constantly.

But topical application isn’t perfect either. Its effects are focal. If you experience arthritis all over your body, you’ll go through your homemade cream pretty quickly.

Combination

Using both oral and topical administration is an excellent way to cover both your bases. Granted, this will use up your CBD oil relatively quickly. If that’s the route you want to take, we recommend Colorado Botanicals 3,000mg broad-spectrum CBD oil. At 100 mg per 1mL, it’s one of the most potent oils on the market and offers excellent value for the price.

If you’re not much of a fan of CBD oil tinctures or topical CBD products, CBD gummies for pain are also another great option.

Best CBD Dosing Guide for Arthritis

Unfortunately, CBD dosing is one of the biggest riddles we still face. There are so many variables involved that assigning set amounts for specific symptoms is a moving target.

CBD also becomes ineffective if your dose is too high, which is why it’s important to start low and increase it gradually. However, there are some general guidelines that ― if followed ― can give you an idea of your eventual dose.

Colorado Botanicals easily has the best CBD dosing guide we’ve seen. It includes a lot of expert content about the topic, along with a handy CBD dosage calculator. Use it if you need help getting started with CBD oil.

It’s important to note that it’s best to consult with your doctor to get the most accurate information about how much CBD to take for your specific medical condition.

Difference between Full Spectrum, Broad Spectrum, and CBD Isolate

Earlier, we took a deep look into terpenes. CBD is the foundation, but terpenes and other cannabinoids expand or enhance cannabidiol’s benefits.

Your CBD product may or may not contain these additional compounds. It all depends on the type of CBD oil you purchase. There are three options: full-spectrum, broad-spectrum, and isolate, each with advantages and disadvantages.

Full-Spectrum

Also referred to as “whole-plant” extract, full-spectrum CBD retains as many terpenes and cannabinoids as possible, but less than 0.3% THC. This complete profile harnesses CBD’s full potential, making it a compelling choice for therapeutic use.

Many consumers and vendors are adamant that full-spectrum is the best option, but it also has flaws that can turn some people away.

For instance, full-spectrum is known to have a strong cannabis taste, making it hard to consume, even with flavoring.

Another problem is THC. Although the content is compliant with federal law, THC is still a controlled substance. Consequently, traces of THC on a drug test could put you in trouble with some employers.

Broad-Spectrum

A lot of CBD oil fans embrace broad-spectrum products ― and for a good reason. Like full-spectrum, broad-spectrum keeps the additional cannabinoids and terpenes ― but has zero THC.

Broad-spectrum offers the best of both worlds. You get the advantages of other terpenes and cannabinoids without any THC, meaning drug tests aren’t a concern.

Unfortunately, broad-spectrum still carries the same “hempy” aroma as full-spectrum CBD oil.

Here is a great video to learn more in-depth about the difference between full-spectrum and broad-spectrum CBD products.

CBD Isolate

CBD isolate is the opposite of full- and broad-spectrum in every major respect. Unlike its counterparts, it is 99% pure CBD, with terpenes and other cannabinoids deliberately filtered out.

Isolate also has the advantage of being flavorless, so it tastes neutral alone and doesn’t affect the flavor of food or drinks.

However, isolate lacks the compounds necessary for the entourage effect. Despite increased purity, this pure CBD product has limited benefits compared to the other choices.

What is the Difference Between Hemp Oil and CBD Oil?

Here is an amazing video covering the difference between hemp oil and CBD oil and why it’s crucial to know the difference between them.

Hemp Oil vs. CBD Oil: Don't Buy The Wrong Product!

Does CBD Have Side Effects?

To date, we don’t know of any severe or dangerous CBD side effects. This can change depending on whether you use certain prescription medications.

Typical adverse effects include:

• Nausea
• Vomiting
• Diarrhea
• Drowsiness
• Fatigue
• Appetite loss

It could be a different story if you use prescription medication. Many medications are metabolized using the same liver enzyme as CBD. Consequently, this can increase side effects and decrease the effectiveness of those drugs.

Other complications could arise as a result of this drug interaction, so speak to your doctor if you take certain medications.

Summary: Buying the Best CBD Oil for Arthritis

In a largely unregulated market, “buyer beware” is the main rule. The CBD industry still struggles with imprecise labeling and substandard products. The responsibility, therefore, falls onto you to find the best brands.

But shopping around in a sea of products is a considerable undertaking, which is why we take care of that.

When buying CBD oil for arthritis, remember to look for some key things:

• Third-party lab testing
• Brands that follow the FDA’s Good Manufacturing Practices (GMP)
• Organic or organically-grown hemp with no chemical fertilizers or pesticides
• Consumer reputation (if any)
• Value

 

*This article is provided by an advertiser. Statements made are not meant to offer medical advice nor to diagnose any condition. Any studies cited here may be preliminary, and may or may not be peer reviewed, and may or may not have sufficient participants to be statistically relevant. Anecdotal accounts should not be taken as scientific results. Products discussed in this article are not designed to diagnose, treat, prevent, or cure any disease. The FDA does not evaluate dietary supplements. Consult your doctor about possible interactions, allergies, and if you are considering using a natural and/or dietary supplements for any condition. Individual results will vary.